Table of Contents
What is thyroglobulin and Antithyroglobulin?
Thyroglobulin is a protein found in thyroid cells. Antithyroglobulin antibody testing is used in the evaluation for thyroid problems. Antithyroglobulin is not normally found in the blood stream. However, 10-20% of healthy individuals have detectable antithyroglobulin levels.
What does high Antithyroglobulin AB mean?
If you have high levels of antithyroglobulin antibodies in your blood, it may be a sign of serious autoimmune disorder, such as Graves’ disease or Hashimoto thyroiditis. In some cases, you may have antithyroglobulin antibodies in your blood without any specific complications.
What is considered a high level of thyroglobulin antibodies?
Higher levels point to autoimmune thyroid disorders. Research also suggests TgAb levels above 40 IU/mL may be associated with an increased risk of thyroid cancer .
What does a positive thyroglobulin antibody mean?
A positive test result means that you have thyroglobulin antibodies in your blood. This may mean you have a problem with your thyroid gland. A positive thyroglobulin antibody test result may also mean that your thyroglobulin test measurement is incorrect.
What happens if thyroglobulin is high?
Your thyroglobulin levels are high and/or have increased over time. This may mean thyroid cancer cells are growing, and/or cancer is starting to spread. Little or no thyroglobulin was found. This may mean that your cancer treatment has worked to remove all thyroid cells from your body.
What causes high thyroglobulin?
Certain factors, such as gene defects, virus infection, iodine intake, stress or destruction of thyroid follicles caused by thyroid nodules (such as patients in high Tg group in the present study) and cancer, can lead to a raise of Tg level (30, 41, 42).
What is the treatment for high thyroid antibodies?
Hyperthyroidism due to Graves’ disease is caused by antibodies attacking the thyroid and turning it on (see Graves’ disease brochure). Antithyroid medication, radioactive iodine, and surgery are all effective treatments and can restore thyroid function to normal.
What causes high thyroglobulin levels?
What are symptoms of high thyroglobulin?
- Fatigue and sluggishness.
- Increased sensitivity to cold.
- Pale, dry skin.
- A puffy face.
- Brittle nails.
- Hair loss.
- Enlargement of the tongue.
How can I lower my thyroid antibodies?
Studies show that taking 200 mcg of selenium per day may help reduce antithyroid peroxidase (TPO) antibodies and improve well-being in people with Hashimoto’s disease ( 25 , 26 ). Zinc. Zinc is essential for thyroid function.
Why are my thyroid antibodies high?
If your results show high levels of antibodies against thyroid peroxidase or thyroglobulin, you may have Hashimoto’s disease. If you have lots of antibodies against the thyroid stimulating hormone receptor, you may have Graves’ disease.
How do you fix high thyroid antibodies?
Beneficial supplements include:
- Selenium. Studies show that taking 200 mcg of selenium per day may help reduce antithyroid peroxidase (TPO) antibodies and improve well-being in people with Hashimoto’s disease ( 25 , 26 ).
- Vitamin D.
- B complex vitamins.